Dr Shahnawaz Jadeja

Dr Shahnawaz Jadeja is a Senior Postdoctoral Research Fellow at the Centre for Arthritis and Rheumatic Diseases affiliated with the School of Medicine, University College Dublin and Molecular Rheumatology Group, Trinity Biomedical Sciences Institute, Trinity College Dublin.

Shahnawaz completed his Ph.D. in Biochemistry from India. His Ph.D. research project was focused on understanding the role of autoimmunity and endoplasmic reticulum (ER) stress in an autoimmune skin disorder, Vitiligo. He explored the role of candidate polymorphisms of genes involved in ER stress, immunity, and melanogenesis. He also examined the role of homocysteine (Hcy) induced Endoplasmic Reticulum stress in in-vitro cultured primary human melanocytes.

After successfully defending his Ph.D. thesis his research interest in autoimmunity motivated him to join Prof. Desmond Tobin at the Charles Institute of Dermatology, UCD to pursue a postdoctoral research project aimed at discovering autoantigens responsible for triggering immune-mediated damage to anagen hair follicles in a non-scarring hair loss disorder ‘Alopecia Areata’. Shahnawaz investigated the putative role of Trichohyalin (TCHH), a protein expressed in hair follicle inner root sheath, as an autoantigen in Alopecia Areata and identified post-translationally modified immunoreactive epitopes. Dr. Jadeja collaborated with Dr. Eddie James and visited his lab at Benaroya Research Institute, Seattle, USA to perform peptide binding and HLA tetramer-based assays for screening of immunoreactive epitopes in Alopecia areata.

Dr. Jadeja was awarded a research grant from Alopecia UK for his research on Alopecia areata in 2021. In addition, to his credit he has presented his research work at several international conferences and published 19 articles and 3 book chapters as a lead author and co-author. Shahnawaz joined Molecular Rheumatology Group in September 2023 and his current research is focused on understanding the Immune-stomal cell interactions for predicting response in Rheumatoid Arthritis.

Google Scholar: https://scholar.google.co.in/citations?user=EXFxS-8AAAAJ&hl=en

LinkedIn: linkedin.com/in/shahnawaz-jadeja-a28ab6195

Twitter (X): @JadejaShahnawaz