Cytokine targeting has become one of the greatest revolutions in modern medicine. A large number of severe and sometimes even lethal inflammatory and autoimmune diseases have become manageable due to selective inhibition of cytokines and cytokine signaling. The development of compounds that selectively inhibit cytokines or interferons has permitted an so far unprecedented molecular characterization of human disease. Cytokines also contribute to cancer development and alterations in tissue homeostasis. Cytokines 2019 will address these developments and provide a comprehensive picture of the current knowledge of cytokine pathways in human disease and the strategies to inhibit, modulate or foster cytokine responses.
Our very own Achilleas Floudas will be speaking about INCREASED T CELL POLYREACTIVITY WITH MARKED ACCUMULATION OF TNF-Α DP (CD4+CD8+) IN THE SYNOVIAL TISSUE OF PRE-RA, ARTHRALGIA SUBJECTS. He will also be presenting three posters.
Poster 1:B and T cell Phenotype and Function in the Synovial Tissue of ACPA+ and ACPA- Rheumatoid Arthritis Patients.
Poster 2: Hypoxia Resistant Pathogenic B cells Accumulate in the RA Synovial Tissue in a CXCR3 Dependent Manner.
Poster 3:Increased T Cell Plasticity with Dysregulation of Tfh, Tph and Treg Cell Responses in Children with JIA and Down Syndrome-associated Arthritis.
For more information please click here.
Patients Awareness Initiative workshops.
The first of 8 National worshops will take place in TBSI TCD Sept 30th, lead by the Molecular Rheumatology group, in collaboration with Arthritis Ireland and the HRB.
The aim of the workshop is to provide opportunities for people living with RA to understand the importance of early diagnosis, the different treatment strategies and how to get involved in research.
- The Workshop will be jointly facilitated by a clinician, a scientific researcher and a patient partner
- Initially attendees will be asked to complete a ‘questionnaire’ which will address patient’s understanding of their disease.
- Following this there will be three presentations which will cover:
- How the diagnosis for patients with inflammatory arthritis is made and what tests are performed, the current therapies available, including how they work, and the risks and side effects.
- The patients perspective, the patient partner will give a presentation on their journey.
- Current research both clinical and scientific, and how patient participation in research can lead to better understanding of disease. Outline how patients can engage in the research programme.
The next two workshops are scheduled for Oct 14th Limerick and Nov 5th Cork. For registration go to eventbrite.
ISR Autumn Meeting will take place on the 26/27 September 2019 in Killashee Hotel, Naas, Co Kildare – PLEASE NOTE CHANGE OF DATE
Registration for this meeting will open on 1 August 2019.
Accommodation in Killashee Hotel can only be reserved through ISR – telephone 01-231 5251. Single Room B/B €107; Twin Room B/B €160
Abstracts will open on the 1 June 2019 and close 09.00 Monday, 29 July 2019.