2019

Enhanced angiogenic function in response to fibroblasts from psoriatic arthritis synovium compared to rheumatoid arthritis.

Fromm S, Cunningham CC, Dunne MR, Veale DJ, Fearon U, Wade SM.

Arthritis Res Ther. 2019 Dec 21;21(1):297

 

 

Insulin Resistant Pathways are associated with Disease Activity in Rheumatoid Arthritis and are Subject to Disease Modification through Metabolic Reprogramming; A Potential Novel Therapeutic Approach.

Gallagher L, Cregan S, Biniecka M, Cunningham C, Veale DJ, Kane DJ, Fearon U, Mullan RH.

Arthritis Rheumatol. 2019 Dec 16

 

Low Density Granulocytes in ANCA Vasculitis Are Heterogenous and Hypo-Responsive to Anti-Myeloperoxidase Antibodies.

Ui Mhaonaigh A, Coughlan AM, Dwivedi A, Hartnett J, Cabral J, Moran B, Brennan K, Doyle SL, Hughes K, Lucey R, Floudas A, Fearon U, McGrath S, Cormican S, De Bhailis A, Molloy EJ, Brady G, Little MA.

Front Immunol. 2019 Nov 7

 

Increased T Cell Plasticity With Dysregulation of Follicular Helper T, Peripheral Helper T, and Treg Cell Responses in Children With Juvenile Idiopathic Arthritis and Down Syndrome-Associated Arthritis.

Foley C, Floudas A, Canavan M, Biniecka M, MacDermott EJ, Veale DJ, Mullan RH, Killeen OG, Fearon U.

Arthritis Rheumatol. 2019 Oct 27

 

Association of the Rheumatoid Arthritis Severity Variant rs26232 with the Invasive Activity of Synovial Fibroblasts.

Dorris ER, Linehan E, Trenkmann M, Veale DJ, Fearon U, Wilson AG.

Cells. 2019 Oct 22;8(10). 

 

Dysregulated miR-125a promotes angiogenesis through enhanced glycolysis. 

Wade SM, Ohnesorge N, McLoughlin H, Biniecka M, Carter SP, Trenkman M, Cunningham CC, McGarry T, Canavan M, Kennedy BN, Veale DJ, Fearon U.

EBioMedicine. 2019 Sep

 

STAT3 Mediates the Differential Effects of Oncostatin M and TNFα on RA Synovial Fibroblast and Endothelial Cell Function. 

Hanlon MM, Rakovich T, Cunningham CC, Ansboro S, Veale DJ, Fearon U, McGarry T.

Front Immunol. 2019 Aug 28

 

Interleukin-6 does not upregulate pro-inflammatory cytokine expression in an ex vivo model of giant cell arteritis. 

O’Neill L, McCormick J, Gao W, Veale DJ, McCarthy GM, Murphy CC, Fearon U, Molloy ES.

Rheumatol Adv Pract. 2019 May 6

 

Angiogenesis in Inflammatory Arthritis.

Balogh E, Biniecka M, Fearon U, Veale DJ, Szekanecz Z.

Isr Med Assoc J. 2019 May

 

Novel gene targets for miRNA146a and miRNA155 in anterior uveitis.

O’Rourke M, Trenkmann M, Connolly M, Fearon U, Murphy CC.

Br J Ophthalmol. 2019 Feb

 

 Cell metabolism as a potentially targetable pathway in RA. 

McGarry T, Fearon U.

Nat Rev Rheumatol. 2019 Feb

 

Autoimmune and angiogenic biomarkers in autoimmune atherosclerosis.  

Balogh E, Pusztai A, Hamar A, Végh E, Szamosi S, Kerekes G, McCormick J, Biniecka M, Szántó S, Szűcs G, Nagy Z, Fearon U, Veale DJ, Szekanecz Z

Clin Immunol. 2019 Feb

 

Association of synovial tissue polyfunctional T-cells with DAPSA in psoriatic arthritis. 

Wade SM, Canavan M, McGarry T, Low C, Wade SC, Mullan RH, Veale DJ, Fearon U.

Ann Rheum Dis. 2019 Jan 9.

 

Performance characteristics and predictors of temporal artery ultrasound for the diagnosis of giant cell arteritis in routine clinical practice in a prospective cohort.

Conway R, O’Neill L, McCarthy GM, Murphy CC, Veale DJ, Fearon U, Killeen RP, Heffernan EJ, Molloy ES.

Clin Exp Rheumatol. 2019 Jan 4

 

Altered expression of microRNA-23a in psoriatic arthritis modulates synovial fibroblast pro-inflammatory mechanisms via phosphodiesterase 4B.

Wade SM, Trenkmann M, McGarry T, Canavan M, Marzaioli V, Wade SC, Veale DJ, Fearon U.

J Autoimmun. 2019 Jan